1859-05-22 : birth in Edinburgh (22th May) 1882 : become a doctor 1890 : move to London 1887 : publish 1st novel "A study in Scarlet" 1893 : death of Sherlock Holmes ("The Final Problem") 1885 : marry Louisa Hawkins 1889 : birth of 1st daughter (Mary Louise) 1892 : birth of 1st son (Kingsley) 1901 : publish 3rd novel "The Hound of the Baskervilles" 1890 : publish 2nd novel "The Sign of Four" 1914 : publish 4th novel "The Valley of Four" 1906 : death of Louisa Hawkins 1907 : marry 2nd wife Jean Leckie 1892 : publish story "The Adventure of The Speckled Band" 1930 : death in Crowborough (7th July)